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National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Major obstetric complications in women with inherited thrombophilia in comparison to the control group of women
 Pechrová, Viktorie ; Koucký, Michal (advisor) ; Čábela, Radek (referee)
Leiden mutation and mutation of the gen for prothrombin are classified as hereditary thrombophilia affecting external cascade's hemocoagulation factors. The higher incidence is in the Europoid. We marked those disorders not only as risk factors for thromboembolism but as risk factors for obstetrics complications as well. This bachelor thesis completes theoretical knowledge of Leiden mutation and mutation of the gen for prothrombin. Afterward, the thesis is focused on obstetrics complications that are associated with those thrombophilias. The analytical part of the thesis is devoted to the association of the mentioned mutations and the higher risk of recurrent pregnancy loss. Meaning that women who carry the such mutation are more likely to have the anamnesis of 2 or more miscarriages compared to women without thrombophilia. First, the hypothesis was set that the women with thrombophilia are going to have more frequent recurrent pregnancy loss compared to the control group without thrombophilia. To verify the hypothesis a retrospective check of the databases was made. The databases were from The Institute of Medical Biochemistry and Laboratory Diagnostics of the General University Hospital and of the First Faculty of Medicine of Charles University, where the group with thrombophilia was taken. The...
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Gestational diabetes mellitus - influence on the course of labor induction
 Janů, Lucie ; Šimják, Patrik (advisor) ; Čábela, Radek (referee)
This bachelor thesis deals with gestational diabetes mellitus and its influence on the course of induction of labor. Gestational diabetes is a disorder of glucose metabolism occurring during pregnancy that disappears spontaneously in the puerperium. It has a fundamental influence on childbirth and increases the risk of numerous obstetric complications. In many women who suffer from gestational diabetes, it is necessary to induce labor from various indications. It is a preventive method using artificial induction of uterine activity to terminate the pregnancy if its continuation increases the risk of possible damage to the mother or the fetus. The study aimed to determine whether GDM affects the course of labor induction compared to women to whom labor was induced from other indications. We intended to find out whether GDM affects the perinatal and neonatal results of labor induction. We also set 12 hypotheses that helped us to fulfill the goals of our work. The research part of the work was retrospective and examined the labor induction in women performed at the Department of Gynecology and Obstetrics, First Faculty of Medicine, Charles University and General University Hospital in Prague between December 2019 and January 2021. We obtained the data to monitor the course and results of labor...
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